Facile synthesis of benzofurans via copper-catalyzed aerobic oxidative cyclization of phenols and alkynes.

نویسندگان

  • Wei Zeng
  • Wanqing Wu
  • Huanfeng Jiang
  • Liangbin Huang
  • Yadong Sun
  • Zhengwang Chen
  • Xianwei Li
چکیده

Regioselective synthesis of polysubstituted benzofurans using a copper catalyst and molecular oxygen from phenols and alkynes in a one-pot procedure has been reported. The transformation consists of a sequential nucleophilic addition of phenols to alkynes and oxidative cyclization. A wide variety of phenols and alkynes can be used in the same manner.

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عنوان ژورنال:
  • Chemical communications

دوره 49 59  شماره 

صفحات  -

تاریخ انتشار 2013